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The original story of the little mermaid is that she must kill the prince in order to be human, and in the end, she loves him too much and kills herself instead.

The artwork is too great not to reblog. 

Ok, ok - important expansion: she only has to kill the Prince because the deal was if he fell in love with her she could be human forever, and he didn’t. By which I mean, he was a good person and genuinely nice to her, but he didn’t fall in love. He fell in love with someone else, also perfectly nice - not the seawitch in disguise, fu Disney. The Mermaid is told she can only return to the sea now if she kills the Prince. She goes into the room where he and his lover lie sleeping and they look so beautiful and happy together that she can’t do it.
That’s why she kills herself. And because it was a noble act she returns to sea as foam.
One moral of the story was that women shouldn’t fundamentally change who they are for love of a man, and in theory Han Christian Anderson wrote it for a ballerina with whom he fell in love. She was marrying someone else who wouldn’t let her dance.



The original story of the little mermaid is that she must kill the prince in order to be human, and in the end, she loves him too much and kills herself instead.

The artwork is too great not to reblog. 

Ok, ok - important expansion: she only has to kill the Prince because the deal was if he fell in love with her she could be human forever, and he didn’t. By which I mean, he was a good person and genuinely nice to her, but he didn’t fall in love. He fell in love with someone else, also perfectly nice - not the seawitch in disguise, fu Disney. The Mermaid is told she can only return to the sea now if she kills the Prince. She goes into the room where he and his lover lie sleeping and they look so beautiful and happy together that she can’t do it.
That’s why she kills herself. And because it was a noble act she returns to sea as foam.
One moral of the story was that women shouldn’t fundamentally change who they are for love of a man, and in theory Han Christian Anderson wrote it for a ballerina with whom he fell in love. She was marrying someone else who wouldn’t let her dance.

The original story of the little mermaid is that she must kill the prince in order to be human, and in the end, she loves him too much and kills herself instead.

The artwork is too great not to reblog. 

Ok, ok - important expansion: she only has to kill the Prince because the deal was if he fell in love with her she could be human forever, and he didn’t. By which I mean, he was a good person and genuinely nice to her, but he didn’t fall in love. He fell in love with someone else, also perfectly nice - not the seawitch in disguise, fu Disney. The Mermaid is told she can only return to the sea now if she kills the Prince. She goes into the room where he and his lover lie sleeping and they look so beautiful and happy together that she can’t do it.

That’s why she kills herself. And because it was a noble act she returns to sea as foam.

One moral of the story was that women shouldn’t fundamentally change who they are for love of a man, and in theory Han Christian Anderson wrote it for a ballerina with whom he fell in love. She was marrying someone else who wouldn’t let her dance.

(Source: xxdardarxx)

medicalschool:

Sickle Cell Anemia

Early twentieth-century descriptions of sickle cell anemia in Western literature noted that sickling was related to low levels of oxygen, and before mid-century Linus Pauling and Harvey Itano demonstrated through protein electrophoresis that the hemoglobin of patients with the disease is different than that of normal individuals. In the subsequent decades, a more complete understanding of the disease was culled. According to modern medicine, sickle cell anemia is caused by a point mutation in one nucleotide within the sequence of 438 bases coding for the hemoglobin beta chain. A shift in the seventeenth nucleotide from a thymine base to an adenine base in the DNA of genes encoding hemoglobin causes a switch in the sixth amino acid, from glutamic acid to valine, in people with sickle cell anemia. The change of this one amino acid results in hemoglobin (generally referred to as hemoglobin S) that responds to oxygen deficiency by stacking into filaments and clustering in red blood cells containing the mutated protein in such a way that their shape is distorted. Initially, cells experiencing the distortion, or sickling, can resume their normal shape when they are reintroduced to oxygen. However, over time, they lose this ability and the sickle shape becomes permanent.

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